Continuous Glucose Profiles in Obese and Normal-Weight PregnantWomen on a Controlled Diet Metabolic determinants of fetal growth
نویسندگان
چکیده
RESULTS—The 24-h glucose area under the curve was higher in obese women than in normalweight women both early and late in pregnancy despite controlled diets. Nearly all fasting and postprandial glycemic parameters were higher in the obese women later in pregnancy, as were fasting insulin, triglycerides, and FFAs. Infants born to obese mothers had greater adiposity. Maternal BMI (r = 0.55, P = 0.01), late average daytime glucose (r = 0.48, P , 0.05), and late fasting insulin (r = 0.49, P , 0.05) correlated with infant percentage body fat. However, early fasting triglycerides (r = 0.67, P , 0.001) and late fasting FFAs (r = 0.54, P , 0.01) were even stronger correlates.
منابع مشابه
Continuous Glucose Profiles in Obese and Normal-Weight Pregnant Women on a Controlled Diet
OBJECTIVE We sought to define 24-h glycemia in normal-weight and obese pregnant women using continuous glucose monitoring (CGM) while they consumed a habitual and controlled diet both early and late in pregnancy. RESEARCH DESIGN AND METHODS Glycemia was prospectively measured in early (15.7 ± 2.0 weeks' gestation) and late (27.7 ± 1.7 weeks' gestation) pregnancy in normal-weight (n = 22) and ...
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